Inside Precision Medicine Marketplace Molecular Diagnostics SureSeq™ CLL + CNV Panel

Oxford Gene Technology
SureSeq™ CLL + CNV Panel

The SureSeq CLL + CNV Panel has been designed in collaboration with recognised cancer experts to detect 12 key genes and 5 chromosomal regions implicated in CLL progression. The SureSeq CLL + CNV Panel alleviates the burden of running multiple assays and streamlines your CLL research to deliver a comprehensive genomic profile for each CLL sample using a single workflow.

The SureSeq CLL + CNV Panel has been designed in collaboration with recognised cancer experts to detect 12 key genes and 5 chromosomal regions implicated in CLL progression to address this genetic heterogeneity. The SureSeq CLL + CNV Panel alleviates the burden of running multiple assays and streamlines your CLL research to deliver a comprehensive genomic profile for each CLL sample using a single workflow. Backed by Interpret, OGT’s complimentary, intuitive and user-friendly software, the panel delivers fast and accurate detection of all SNVs, indels, LOH and CNVs covered by the panel. Following detection, all events can be readily visualised in the user-friendly variant browser, for an effortless translation of all your CLL data into meaningful results.




Oxford Gene Technology

Begbroke Science Park
Begbroke Hill, Woodstock Road Begbroke, Oxfordshire OX5 1PF, UK
+44 (0)1865 856800
https://www.ogt.com





Features & Specs

The SureSeq CLL + CNV Panel offers:

  • Unparalleled uniformity and high depth of coverage – detect low-frequency SNVs and indels with confidence
  • CNV detection ranging from loss of single exons to full chromosome arms and trisomy 12 – profile your samples for CNVs in the 5 most commonly aberrant regions in CLL
  • Time savings – replace multiple assays with a single NGS panel, increasing throughput and reducing turnaround time
  • Complimentary data analysis software – analyse your data with Interpret, OGT’s powerful and easy-to-use analysis solution for accurate identification of all variants and CNVs
Genes ATM, PLCG2, BIRC3, BRAF, TP53, XPO1, SF3B1, KRAS, MYD88, SAMHD1, NOTCH1 and BTK
CNVs CNVs 17p (covering TP53), 11q (covering ATM), 13q (covering RB1/DLEU2/DLEU7), 6q (6q23.2-6q23.3 covering MYB) and Trisomy 12
Sample Tracking CXCR4 and SRY + 24 SNP profiling panel

The SureSeq CLL + CNV Panel targets the 5 most common chromosomal regions implicated in CLL and 14 genes, including 2 genes and 24 SNPs for easy sample tracking.

Features & Specs

The SureSeq CLL + CNV Panel offers:

  • Unparalleled uniformity and high depth of coverage – detect low-frequency SNVs and indels with confidence
  • CNV detection ranging from loss of single exons to full chromosome arms and trisomy 12 – profile your samples for CNVs in the 5 most commonly aberrant regions in CLL
  • Time savings – replace multiple assays with a single NGS panel, increasing throughput and reducing turnaround time
  • Complimentary data analysis software – analyse your data with Interpret, OGT’s powerful and easy-to-use analysis solution for accurate identification of all variants and CNVs
Genes ATM, PLCG2, BIRC3, BRAF, TP53, XPO1, SF3B1, KRAS, MYD88, SAMHD1, NOTCH1 and BTK
CNVs CNVs 17p (covering TP53), 11q (covering ATM), 13q (covering RB1/DLEU2/DLEU7), 6q (6q23.2-6q23.3 covering MYB) and Trisomy 12
Sample Tracking CXCR4 and SRY + 24 SNP profiling panel

The SureSeq CLL + CNV Panel targets the 5 most common chromosomal regions implicated in CLL and 14 genes, including 2 genes and 24 SNPs for easy sample tracking.