Inside Precision Medicine Marketplace Translational Research 12-plex Immunophenotyping Panel

Ultivue
12-plex Immunophenotyping Panel

With the advent of immunology-based strategies to combat tumors, single marker assays are not sufficient to verify response. This may be due to lack of proper identification of cellular phenotypes within samples. By understanding the complex phenotypes associated with the tumor immune microenvironment that may be present, researchers gain a more complete understanding of mechanisms of action and cellular phenotypes that may be promoting or hindering response. The 12-Plex Immunophenotyping Panel reveals a comprehensive view of the immune system activity at play within the tumor microenvironment. Through the use of InSituPlex® technology, whole-slide imaging, uninhibited antibody co-localization, and detection of co-expression of markers allow for 4,096 potential cell phenotypes coupled with same slide H&E analysis. 




Ultivue

763D, Concord Ave
Cambridge, MA 02138
(617) 945-2662
https://www.ultivue.com





Features & Specs

  • Whole-slide imaging 
    • View the entire sample stained with 12 markers and nuclear counterstain removing bias of pre-defined ROIs 
  • Same-slide H&E 
    • Gather tissue multiplexing and tissue morphology data from the same sample 
    • Co-registered and fused images created using UltiStacker™ software  
  • High co-localization and co-expression of markers 
    • InSituPlex® technology allows for deep single-cell characterization 
    • 4,096 potential phenotypes analyzed simultaneously 
  • Pathology and Biomarker Analytics 
    • Distance mapping and UMAP analysis 
    • Biological insights into unique phenotypes 
    • Markers: CD3, CD4, CD8, CD20, CD56, CD68, CD163, Granzyme B, FoxP3, PD-1, PD-L1,CK/Sox10 

Features & Specs

  • Whole-slide imaging 
    • View the entire sample stained with 12 markers and nuclear counterstain removing bias of pre-defined ROIs 
  • Same-slide H&E 
    • Gather tissue multiplexing and tissue morphology data from the same sample 
    • Co-registered and fused images created using UltiStacker™ software  
  • High co-localization and co-expression of markers 
    • InSituPlex® technology allows for deep single-cell characterization 
    • 4,096 potential phenotypes analyzed simultaneously 
  • Pathology and Biomarker Analytics 
    • Distance mapping and UMAP analysis 
    • Biological insights into unique phenotypes 
    • Markers: CD3, CD4, CD8, CD20, CD56, CD68, CD163, Granzyme B, FoxP3, PD-1, PD-L1,CK/Sox10